scope method state nucleus matched_residues r2_predictive pearson_r pearson_r_squared rmse_ppm mae_ppm bias_ppm original_frame_count_matches all_available AF3 Original N 22 0.7858123374687083 0.9005997031777169 0.8110798253637918 1.2707636795772175 0.9849509617129025 -0.2835117492288297 True all_available AF3 Relaxed N 22 0.6330101745325204 0.8486274813212651 0.7201686020536742 1.6633918903479783 1.4356458934437135 -0.7071411604447814 True all_available AF3 Original HN 22 -1.5280979069194869 0.33957923263367656 0.11531405523607663 0.45304848675032006 0.39322559426602033 0.3192160678642658 True all_available AF3 Relaxed HN 22 0.11453631235576034 0.7785465987949274 0.6061348064951496 0.26812241190961955 0.22513395755941223 -0.14424377515099251 True all_available AF3 Original HA 0 True all_available AF3 Relaxed HA 0 True all_available AF3 Original CA 27 0.949301570632426 0.9769418995309049 0.9544154750590528 0.7184982314051735 0.5918080136024142 0.12720093147038844 True all_available AF3 Relaxed CA 27 0.7856376596133934 0.9291826927519137 0.8633804765096972 1.477415652571151 0.9998744285018356 0.6411454048156736 True all_available AF3 Original CB 27 0.9972674358712166 0.998930565800098 0.9978622752897038 0.6702340362397536 0.5493441265617058 -0.25448236859615736 True all_available AF3 Relaxed CB 27 0.9969143816266216 0.998614095491279 0.9972301117138653 0.7122171106282468 0.5590411589587182 -0.1908424077210611 True all_available AF3 Original C 26 0.0037994880849214763 0.7647322002584598 0.584815338112145 1.19247369888714 0.9301234070320944 0.7344247274681871 True all_available AF3 Relaxed C 26 0.2864482812293593 0.6637234553876394 0.4405288252317078 1.0092253647543918 0.8304922215388374 0.33808392920860797 True all_available Boltz Original N 22 0.7994015293360459 0.9094645215746022 0.8271257160029201 1.2297911876871876 0.9346059154260389 -0.34915818023443923 True all_available Boltz Relaxed N 22 0.6801407121523528 0.876385896075286 0.7680522388396821 1.5529127326387888 1.2257332365358038 -0.6660584252556574 True all_available Boltz Original HN 22 -1.4338017580237858 0.37984475957224395 0.14428204137449582 0.4445190114181942 0.3881326417484956 0.333009027557805 True all_available Boltz Relaxed HN 22 0.2625071568066999 0.7845740590250772 0.6155564540950852 0.24469587300455553 0.21108568067719843 -0.09689594226582794 True all_available Boltz Original HA 0 True all_available Boltz Relaxed HA 0 True all_available Boltz Original CA 27 0.9536070487783714 0.9790184600593442 0.9584771451369698 0.6873128302748259 0.5739323461091638 0.07253139114723747 True all_available Boltz Relaxed CA 27 0.770351447848626 0.9251574075591061 0.855916228761486 1.5291859768093372 1.043774755309791 0.6568586926304589 True all_available Boltz Original CB 27 0.997296543873834 0.9989237373003922 0.997848632942183 0.66665472282509 0.5216349528971483 -0.18845409085042775 True all_available Boltz Relaxed CB 27 0.9976221284205778 0.9989230674165998 0.9978472946169887 0.625223790823663 0.42997924671869653 -0.1901862530099731 True all_available Boltz Original C 26 0.03534549955809019 0.7831067016412258 0.6132561061553998 1.1734411831128277 0.9224939024390656 0.7312672205843154 True all_available Boltz Relaxed C 26 0.39272075428068887 0.7294906791631516 0.5321566509859161 0.9310428049845239 0.7556591549241722 0.37113467630934865 True all_available AlphaFlow Original N 22 0.817830440588891 0.9196701814625349 0.8457932426713318 1.1719402542580262 0.9785759545454359 -0.4131835909090808 True all_available AlphaFlow Relaxed N 22 0.7710607860615731 0.9247608504393946 0.8551826305053923 1.313795171851683 1.036383489088581 -0.765809793992477 True all_available AlphaFlow Original HN 22 -1.3914801072959522 0.37217716968379366 0.13851584563383934 0.44063716657209917 0.39314240909091525 0.3419122272727224 True all_available AlphaFlow Relaxed HN 22 0.5887106180303228 0.8706330485549072 0.7580019052360114 0.18273489518469463 0.1587695001255381 -0.11603477100892491 True all_available AlphaFlow Original HA 0 True all_available AlphaFlow Relaxed HA 0 True all_available AlphaFlow Original CA 27 0.967672744087353 0.9843542460506864 0.9689532817180153 0.5737370175592877 0.43087174074074297 0.11395796296296289 True all_available AlphaFlow Relaxed CA 27 0.9294266513170889 0.9752574618996378 0.9511271169909234 0.8477129416929402 0.6213568413345901 0.46857879172431105 True all_available AlphaFlow Original CB 27 0.9981415718763926 0.9994353178808238 0.9988709546275434 0.5527314568879853 0.4505891481481703 -0.21365255555557205 True all_available AlphaFlow Relaxed CB 27 0.9983236354248302 0.9995096525727326 0.9990195455860647 0.5249591799225406 0.42027131681089097 -0.3382343491448303 True all_available AlphaFlow Original C 26 0.2801166638255217 0.8377301425045848 0.7017917916607519 1.0136930970631635 0.7663702307692415 0.6584742307692568 True all_available AlphaFlow Relaxed C 26 0.7102975722103053 0.8615157409355451 0.7422093718797211 0.6430599999311271 0.5148998319185694 0.21342578711876678 True all_available BioEmu Original N 22 0.5759121363512796 0.8984006815504095 0.8071237846102404 1.788115179416271 1.5571465909089781 -1.3200454545455287 True all_available BioEmu Relaxed N 22 0.8668632897898446 0.9589116122681233 0.9195114801426516 1.0018817796562616 0.7808311750943759 -0.6285693647251042 True all_available BioEmu Original HN 22 -18.886712467744253 0.0439984600839228 0.001935864489756548 1.2706596435966278 1.1794921875000055 1.1461285511363564 True all_available BioEmu Relaxed HN 22 0.7219541168732575 0.916112804149222 0.8392626699261508 0.15024705708118716 0.1205329410093002 -0.09684529190775852 True all_available BioEmu Original HA 0 True all_available BioEmu Relaxed HA 0 True all_available BioEmu Original CA 27 0.8956605795208497 0.981987612628854 0.9642996713565163 1.0307483802215585 0.9194271219135194 0.8297913966049969 True all_available BioEmu Relaxed CA 27 0.9371476191728101 0.9740386115530202 0.9487512167961354 0.7999987667698466 0.5871670186318235 0.33144665789111527 True all_available BioEmu Original CB 27 0.9911256342085517 0.998955728384199 0.9979125472716055 1.207841535547361 1.0329761574074088 -1.0329761574074088 True all_available BioEmu Relaxed CB 27 0.9986871319499764 0.9995284732569888 0.9990571688514469 0.4645707225951781 0.3633341129052378 -0.24571691087659453 True all_available BioEmu Original C 26 -0.20440775668274913 0.8803039576254413 0.7749350578110148 1.3111796514261995 1.1878419871794348 1.1721427884614877 True all_available BioEmu Relaxed C 26 0.7455785950045244 0.8702560243468558 0.7573455479119953 0.6026320872909267 0.49240466546526396 0.11900273490569956 True all_available idpSAM Original N 22 0.8081302185905813 0.9086623996083417 0.8256673564619897 1.2027375172935026 0.881585227272764 -0.3609829545454604 True all_available idpSAM Relaxed N 22 0.8149776606535797 0.9208308504283774 0.8479294551006488 1.1810809146292263 0.9201355183789546 -0.49465101301346565 True all_available idpSAM Original HN 22 0.33328855960605963 0.6105613688886081 0.372785185179131 0.23265730511028954 0.1950473636363648 -0.05035190909091014 True all_available idpSAM Relaxed HN 22 0.45465725036036675 0.7199080942562854 0.5182676641757168 0.21041781734350198 0.17367361846919663 -0.07122472114305835 True all_available idpSAM Original HA 0 True all_available idpSAM Relaxed HA 0 True all_available idpSAM Original CA 27 0.9688202209109051 0.9858289802042729 0.9718587782105966 0.5634624350918638 0.4112171481481397 -0.15367440740740895 True all_available idpSAM Relaxed CA 27 0.9701746531057794 0.9856166735852978 0.9714402272493475 0.5510883151407988 0.4025907883837705 -0.11337813856971085 True all_available idpSAM Original CB 27 0.9987317542528958 0.9994329460567085 0.9988662136635916 0.4566074619631713 0.34711888888889664 0.13788251851852062 True all_available idpSAM Relaxed CB 27 0.9987890938483655 0.9993994229425132 0.9987992065778283 0.44616606994650376 0.36334806675876646 -0.03976430833344198 True all_available idpSAM Original C 26 0.6634085281601969 0.9183305082309544 0.843330922347723 0.6931496093863827 0.5666990384615644 -0.4185785769230786 True all_available idpSAM Relaxed C 26 0.6739445353771977 0.9149529983572894 0.837138989202994 0.6822148528346464 0.5679839894491869 -0.4181786206173235 True all_available IDPFold Original N 22 0.5628735350913896 0.8841053850810762 0.781642331929358 1.8153949299861918 1.520517409091193 -1.280395196969372 True all_available IDPFold Relaxed N 22 0.7559138415527704 0.9375594265614353 0.8790176783342074 1.3565604274255716 1.1010832875205698 -0.9561535818569737 True all_available IDPFold Original HN 22 -13.296184188030185 0.06405896435928787 0.004103550914784514 1.0773524584454868 0.9780194393939248 0.94465580303032 True all_available IDPFold Relaxed HN 22 0.578701805165824 0.8773246232047209 0.7696984944813056 0.18494497619701777 0.1588871673044596 -0.12142334335416666 True all_available IDPFold Original HA 0 True all_available IDPFold Relaxed HA 0 True all_available IDPFold Original CA 27 0.8144451276278919 0.9721746257228768 0.9451235028994156 1.3745629452039911 1.214792469135955 1.1262739506171402 True all_available IDPFold Relaxed CA 27 0.8556330304528723 0.9538710820923232 0.9098700412519796 1.2124459047674137 0.8350481594101614 0.6868191358744274 True all_available IDPFold Original CB 27 0.9891311117031686 0.9985133593264377 0.9970289287533677 1.3366997286984592 1.1195610000000327 -1.1194024567901588 True all_available IDPFold Relaxed CB 27 0.9975547577432031 0.999124006659564 0.9982487806834606 0.6340189570113866 0.4823604367020797 -0.3335945444830695 True all_available IDPFold Original C 26 -0.805603960544282 0.8376836464941865 0.7017138916037972 1.6054126403551372 1.404701641025394 1.404701641025394 True all_available IDPFold Relaxed C 26 0.5514166552766544 0.7967582922373874 0.634823776249038 0.8001971516805142 0.6400277561280304 0.3104267990716035 True interior_2-27 AF3 Original N 21 0.7852835645707055 0.901425631469434 0.8125681690700678 1.2990255850526211 1.0175938598992142 -0.3112718372778384 True interior_2-27 AF3 Relaxed N 21 0.6321574433812358 0.8521414722775287 0.7261450887753141 1.700262775286066 1.4848180792672288 -0.7600064533778611 True interior_2-27 AF3 Original HN 21 -1.8358388907667726 0.43589946522393413 0.19000834378251177 0.4567418511081931 0.3944744320882057 0.35189302347685597 True interior_2-27 AF3 Relaxed HN 21 0.05856957922149453 0.7834370997997749 0.6137736893426825 0.26316258544402465 0.21886947883878438 -0.13412738298234467 True interior_2-27 AF3 Original HA 0 True interior_2-27 AF3 Relaxed HA 0 True interior_2-27 AF3 Original CA 25 0.9517864775631637 0.9785331958776285 0.9575272154344854 0.722100936907942 0.5885648702594728 0.18796479041915404 True interior_2-27 AF3 Relaxed CA 25 0.7847088530734972 0.9310123910551344 0.8667840722981985 1.5259017225082823 1.033687551422119 0.7386138685607909 True interior_2-27 AF3 Original CB 25 0.9971880859816824 0.9988957146824551 0.9977926488109727 0.6930413937535037 0.5768438323353239 -0.2583931337325315 True interior_2-27 AF3 Relaxed CB 25 0.9968028604251514 0.9985651989957243 0.9971324566453704 0.738990668640107 0.5931172054290776 -0.195462554092408 True interior_2-27 AF3 Original C 25 0.003040728471251586 0.7681788448452782 0.5900987376678261 1.2157776613655333 0.9618221956087257 0.7582955688622621 True interior_2-27 AF3 Relaxed C 25 0.2860461329943256 0.6640699035478547 0.440988836798057 1.0288463619711687 0.858225805053712 0.3461211810302734 True interior_2-27 Boltz Original N 21 0.7989207162043249 0.9105502460662603 0.8291017506113273 1.2570968129008504 0.965117139538752 -0.37977857972460616 True interior_2-27 Boltz Relaxed N 21 0.679392399247968 0.8794587991747751 0.7734477794459373 1.5873473362799355 1.2662375425342236 -0.7156394364854024 True interior_2-27 Boltz Original HN 21 -1.7268122175829372 0.49779801953727293 0.24780286825523115 0.4478758508500917 0.38913895802223175 0.36634279077484505 True interior_2-27 Boltz Relaxed HN 21 0.23697404428450042 0.8010309649945166 0.6416506068800466 0.23691888844185865 0.2034136372653728 -0.08378629226298465 True interior_2-27 Boltz Original HA 0 True interior_2-27 Boltz Relaxed HA 0 True interior_2-27 Boltz Original CA 25 0.9561386387688292 0.9803080467246007 0.961003866473002 0.6887387697025623 0.5694043554006822 0.12877648083623114 True interior_2-27 Boltz Relaxed CA 25 0.7693718626071949 0.9269737868670175 0.8592804015385788 1.579318138755738 1.0793563458294486 0.7573277779460212 True interior_2-27 Boltz Original CB 25 0.9972118497744543 0.9988925465169944 0.9977863194872059 0.6901066959433408 0.5483283275261331 -0.18849299651567492 True interior_2-27 Boltz Relaxed CB 25 0.9975428961278591 0.9988822130943698 0.9977656756363059 0.6478432147861376 0.4514359832439355 -0.1924595500385142 True interior_2-27 Boltz Original C 25 0.034668371315246804 0.7864402940163272 0.6184883360524872 1.1963375079345402 0.9536688153310331 0.7547930662020929 True interior_2-27 Boltz Relaxed C 25 0.392400413783064 0.7301453106228757 0.5331121746245756 0.9491266892597819 0.7806976096463597 0.3807921518869432 True interior_2-27 AlphaFlow Original N 21 0.8174392568158845 0.9210372745815466 0.8483096611686033 1.1978122712814927 1.0112159999999821 -0.4468178095237972 True interior_2-27 AlphaFlow Relaxed N 21 0.7708023734045742 0.9287282866967563 0.8625362305106924 1.3421161999549833 1.067510184878397 -0.8205018259684257 True interior_2-27 AlphaFlow Original HN 21 -1.6778792671226435 0.521315497794085 0.27176984824029465 0.4438390675964731 0.39438728571428616 0.37566995238095335 True interior_2-27 AlphaFlow Relaxed HN 21 0.6150507197525735 0.878715061247867 0.7721401588638427 0.16827972227568583 0.14851600102015888 -0.10374628480275462 True interior_2-27 AlphaFlow Original HA 0 True interior_2-27 AlphaFlow Relaxed HA 0 True interior_2-27 AlphaFlow Original CA 25 0.97044003120693 0.9866163340265997 0.9734117905680869 0.5654125750653766 0.4149196400000136 0.17349643999998876 True interior_2-27 AlphaFlow Relaxed CA 25 0.9310150593622128 0.9794567835324726 0.9593355908077769 0.8637551007441256 0.6242075570678708 0.5529229266357425 True interior_2-27 AlphaFlow Original CB 25 0.9980890759176719 0.9994241445730145 0.9988486207555018 0.5713205862692436 0.4722448000000013 -0.21635327999999518 True interior_2-27 AlphaFlow Relaxed CB 25 0.9982696642299451 0.9995014828357198 0.9990032141908027 0.5436549532314844 0.4424143579101569 -0.3538144328308114 True interior_2-27 AlphaFlow Original C 25 0.27970849123962893 0.8406227438339244 0.7066465974508758 1.0334027160953299 0.7915278799999976 0.6793160400000136 True interior_2-27 AlphaFlow Relaxed C 25 0.7104360524442929 0.8614200163798456 0.7420444446198534 0.6552208298497706 0.5300081146240234 0.21647510803222872 True interior_2-27 BioEmu Original N 21 0.5746414672920659 0.9079135250969538 0.8243069690539769 1.8283638885352806 1.6134392857142603 -1.4007619047618898 True interior_2-27 BioEmu Relaxed N 21 0.8671070282732588 0.9621283380904807 0.9256909389567504 1.0219651049773022 0.7995579276700288 -0.6769569235694267 True interior_2-27 BioEmu Original HN 21 -21.906138885109776 0.2629846138012631 0.0691609070961995 1.298093500503395 1.2181822916666658 1.2181822916666658 True interior_2-27 BioEmu Relaxed HN 21 0.7638655558297811 0.9274606468502262 0.8601832514558401 0.13179826737385347 0.1089818755264013 -0.08416624313431001 True interior_2-27 BioEmu Original HA 0 True interior_2-27 BioEmu Relaxed HA 0 True interior_2-27 BioEmu Original CA 25 0.8968153293809713 0.9895544516436685 0.9792180127678015 1.0563821851942603 0.9451812916666696 0.9439747083333279 True interior_2-27 BioEmu Relaxed CA 25 0.9389080787500618 0.9768723796534133 0.9542796461297225 0.812840565296748 0.5869396867719047 0.40516308387286926 True interior_2-27 BioEmu Original CB 25 0.9907916451535406 0.9990584829114767 0.9981178522773814 1.254149125500188 1.1027742499999986 -1.1027742499999986 True interior_2-27 BioEmu Relaxed CB 25 0.9986491670924502 0.9995130389645059 0.999026315060062 0.4803513021276661 0.3802046662077045 -0.2531780880167698 True interior_2-27 BioEmu Original C 25 -0.2054367868206659 0.894065339819759 0.7993528318670211 1.3368653639939614 1.2298756666666544 1.2135484999999893 True interior_2-27 BioEmu Relaxed C 25 0.7457522492907351 0.8700916833221073 0.7570595373862983 0.6139655607225245 0.5066663689084475 0.11832836112650057 True interior_2-27 idpSAM Original N 21 0.8079880749331885 0.9100206744138627 0.8281376278606615 1.2284264569105396 0.9060663333333694 -0.3956717619047706 True interior_2-27 idpSAM Relaxed N 21 0.8149348950875055 0.9230608873155863 0.8520414016918376 1.2060000598709175 0.9457695129318818 -0.5363878056697013 True interior_2-27 idpSAM Original HN 21 0.328456842056033 0.6036647808905358 0.36441116768761855 0.22226290940728569 0.18568285714285868 -0.034097142857144276 True interior_2-27 idpSAM Relaxed HN 21 0.4613756437379214 0.7107804577230976 0.5052088590810562 0.19905496960417024 0.16400057135056945 -0.05667315510413886 True interior_2-27 idpSAM Original HA 0 True interior_2-27 idpSAM Relaxed HA 0 True interior_2-27 idpSAM Original CA 25 0.9712662876607386 0.9864250968739581 0.9730344717427976 0.5574543995863186 0.39586719999998965 -0.11772104000000042 True interior_2-27 idpSAM Relaxed CA 25 0.9726701857086042 0.9865028762782846 0.9731879249053285 0.5436655544994947 0.3855755237207819 -0.07322586192159747 True interior_2-27 idpSAM Original CB 25 0.9986987393870054 0.9994441890321644 0.9988886869901606 0.47145505718030384 0.36152152000000454 0.16228000000000606 True interior_2-27 idpSAM Relaxed CB 25 0.9987584998439882 0.9993824204480645 0.9987652223006319 0.4605020263802062 0.3779245278031654 -0.028454068703814953 True interior_2-27 idpSAM Original C 25 0.6634326166598834 0.9287120183486007 0.8625060130251317 0.706401258486418 0.5841828000000282 -0.4405059200000005 True interior_2-27 idpSAM Relaxed C 25 0.6738737418862035 0.923501441411701 0.8528549122894894 0.6953578068548443 0.5861809156496577 -0.4394281988195132 True interior_2-27 IDPFold Original N 21 0.5615376024502641 0.8929651556311632 0.7973867691713875 1.856313134761194 1.5750658571428378 -1.359223539682516 True interior_2-27 IDPFold Relaxed N 21 0.7557134058850437 0.9433585533502118 0.8899253601790044 1.3855904384964708 1.1339654294559958 -1.0212351003680975 True interior_2-27 IDPFold Original HN 21 -15.442283183518317 0.24887830610439804 0.06194041124939445 1.099793357945634 1.0071156031746045 1.0071156031746045 True interior_2-27 IDPFold Relaxed HN 21 0.5923218600771025 0.8827214745171988 0.7791972015738178 0.17317641425967553 0.14977222950526156 -0.11052441393828802 True interior_2-27 IDPFold Original HA 0 True interior_2-27 IDPFold Relaxed HA 0 True interior_2-27 IDPFold Original CA 25 0.8142320038872166 0.9817187738273593 0.9637717508850938 1.4174212054127993 1.2641758666666716 1.2641758666666716 True interior_2-27 IDPFold Relaxed CA 25 0.8558358529118215 0.9580176822496459 0.9177978795029835 1.2486539950793347 0.8560134510958958 0.7876032278114602 True interior_2-27 IDPFold Original CB 25 0.9887185034966617 0.9986364209749822 0.9972747012977218 1.3881663509387883 1.1962858800000187 -1.1961146533333549 True interior_2-27 IDPFold Relaxed CB 25 0.9974701561830599 0.9990971956566382 0.9981952063689589 0.6573626299965522 0.5095845640145601 -0.34891740041802904 True interior_2-27 IDPFold Original C 25 -0.8073994074627993 0.852926804354491 0.7274841335863641 1.6369767792014094 1.455409706666719 1.455409706666719 True interior_2-27 IDPFold Relaxed C 25 0.551350740681455 0.797029700928985 0.6352563441629472 0.8155844345856856 0.6601511629074298 0.3173661675687458 True