Intrinsic Disorder
How flexible regions of p53 and Tau respond to molecular context and chemical modifications.
The structural dynamics of p53
Exploring the conformational landscapes of four intrinsically disordered regions.
Explore project
Proline-rich regions
Investigating protein flexibility and interactions in p53 and Tau.
Explore project
Protein phosphorylation
Understanding how chemical modifications influence protein structure and dynamics.
Explore projectOrphan Nuclear Receptors
Investigating the interfaces and interactions that govern nuclear receptor function.
Peptidomimetics
A current research focus connecting peptide-inspired molecular design with pharmaceutical modeling.
Supporting computational methods
Dimensionality reduction, clustering, and NMR prediction provide tools for investigating molecular ensembles.
Interested in working together?
Get in touch to discuss research and collaborations.
Contact Michael ↗