Quantum Pharmacy

Research projects

Explore the biological questions and computational methods behind my work.

The Dark Proteome (IDPs)

While much of the ordered protein machinery has been mapped, the Dark Proteome represents a significant challenge for targeted therapeutics.

Exploring the Disordered Regions of P53

Exploring the conformational landscapes of four intrinsically disordered regions.

Explore project

Untangling the Proline-Rich Regions of Tau

Investigating protein flexibility and interactions in p53 and Tau.

Explore project

Untangling Mysteries in CHCHD2 Fibrils

Awaiting publication

Investigating the origins of CHCHD2 amyloid fibril nucleation.

Explore project

Orphan Nuclear Receptors

Many proteins represent a complex challenge for scientists, as not even a natural ligand has been found. Complex challenges require elegant solutions.

Deorphanizing NR2F6

Investigating potential binding partners and approaches to understanding NR2F6 recognition.

Explore project

Peptidomimetic Modeling of the NR2F6:NSD1 Interactions

Modeling peptide-inspired approaches to NR2F6–NSD1 interactions.

Explore project

PXR: New Allosteric Site

Investigating an allosteric site in PXR and its relevance to pharmaceutical modeling.

Explore project

Peptidomimetics

While small-molecule ligands are frequently tested in large quantities using HITS, peptidomimetics present a unique solution – hijacking biology itself.